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During this process, the double-stranded DNA separates, and each strand is copied to kind a brand new double strand. This "sticking" can interfere with the normal operate of DNA. Now let's look on the intrinsic and exterior factors that may change these DNA molecules. External physical agents, particularly radiation, are highly effective mutagens. Chemical agents introduce one other dimension of exterior mutations. Mutations attributable to factors like transposons can consequence in the creation of a mutant allele, which is a variant form of a gene. Some chemicals, like 5-Bromouracil, can trick our DNA and cause errors. Tobacco, ultraviolet light and different chemicals are all potential enemies of DNA. Ultraviolet (UV) radiation, as an illustration, induces the formation of pyrimidine dimers, notably thymine dimers, that distort the DNA construction. This particular construction ensures accurate replication throughout cell division. In some cases, the structure of DNA constructing blocks can momentarily change, a phenomenon often known as tautomeric shifts.